RoyalEpigen P5 is a novel creation from Mibelle Biochemistry. This new, biologically active peptide is said to activate skin regeneration and improve skin glow.

With age, epidermal growth factor (EGF) activity declines, leading to reduced wound healing capabilities. Royalactin, a protein found in bee royal jelly, interacts with the EGF receptor and other signaling pathways leading to epigenetic effects, according to Mibelle. Activation of the EGF receptor promotes tissue regeneration via cell proliferation and migration, as well as protein turnover through proteasome activation and protein neosynthesis.